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Heterogeneous gene expression from the inactive X chromosome: An X-linked gene that escapes X inactivation in some human cell lines but is inactivated in others
In mammalian females, most genes on one X chromosome are transcriptionally silenced as a result of X chromosome inactivation. Whereas it is well established that some X-linked genes “escape” X inactivation and are expressed from both active (Xa) and inactive (Xi) X chromosomes, most models for the c...
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Autores principales: | , |
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Formato: | Artigo |
Lenguaje: | Inglês |
Publicado: |
The National Academy of Sciences
1999
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Materias: | |
Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC22091/ https://ncbi.nlm.nih.gov/pubmed/10377420 |
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