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The Influence of Diabetes Mellitus on Glucuronidation and Sulphation of Paracetamol in Patients with Febrile Neutropenia

BACKGROUND AND OBJECTIVES: Numerous studies have confirmed the influence of diabetes mellitus on the pharmacokinetics of drugs. Paracetamol (APAP) is an antipyretic that is commonly used in febrile neutropenia (FN) therapy. APAP is chiefly metabolised by glucuronidation and sulphation. This study as...

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Detalhes bibliográficos
Publicado no:Eur J Drug Metab Pharmacokinet
Main Authors: Stachowiak, Anna, Szałek, Edyta, Karbownik, Agnieszka, Łojko, Anna, Porażka, Joanna, Przewoźna, Iwona, Grabowski, Tomasz, Wolc, Anna, Grześkowiak, Edmund
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6418056/
https://ncbi.nlm.nih.gov/pubmed/30187443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13318-018-0508-4
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