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Insulin signaling in LepR cells modulates fat and glucose homeostasis independent of leptin
Hypothalamic neurons detect changes in circulating hormones such as leptin and insulin and put forward outputs to sustain energy and glucose homeostasis. Because leptin and insulin receptors colocalize in ~40–60% of neurons in the hypothalamus, we characterized the metabolic phenotype of mice with s...
Gardado en:
| Publicado en: | Am J Physiol Endocrinol Metab |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Physiological Society
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6417687/ https://ncbi.nlm.nih.gov/pubmed/30376348 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00287.2018 |
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