The LepR-mediated leptin transport across brain barriers controls food reward

OBJECTIVE: Leptin is a key hormone in the control of appetite and body weight. Predominantly produced by white adipose tissue, it acts on the brain to inhibit homeostatic feeding and food reward. Leptin has free access to circumventricular organs, such as the median eminence, but entry into other br...

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Bibliografske podrobnosti
izdano v:Mol Metab
Main Authors: Di Spiezio, Alessandro, Sandin, Elvira Sonia, Dore, Riccardo, Müller-Fielitz, Helge, Storck, Steffen E., Bernau, Mareike, Mier, Walter, Oster, Henrik, Jöhren, Olaf, Pietrzik, Claus U., Lehnert, Hendrik, Schwaninger, Markus
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2017
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5985039/
https://ncbi.nlm.nih.gov/pubmed/29254602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2017.12.001
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