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Mechanisms of DNA-reactive and epigenetic chemical carcinogens: applications to carcinogenicity testing and risk assessment

Chemicals with carcinogenic activity in either animals or humans produce increases in neoplasia through diverse mechanisms. One mechanism is reaction with nuclear DNA. Other mechanisms consist of epigenetic effects involving either modifications of regulatory macromolecules or perturbation of cellul...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Toxicol Res (Camb)
मुख्य लेखकों: Kobets, Tetyana, Iatropoulos, Michael J., Williams, Gary M.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Royal Society of Chemistry 2018
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6417487/
https://ncbi.nlm.nih.gov/pubmed/30997017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8tx00250a
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