Chicken Fetal Liver DNA Damage and Adduct Formation by Activation-Dependent DNA-Reactive Carcinogens and Related Compounds of Several Structural Classes

The chicken egg genotoxicity assay (CEGA), which utilizes the liver of an intact and aseptic embryo-fetal test organism, was evaluated using four activation-dependent DNA-reactive carcinogens and four structurally related less potent carcinogens or non-carcinogens. In the assay, three daily doses of...

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Detalhes bibliográficos
Publicado no:Toxicol Sci
Main Authors: Williams, Gary M., Duan, Jian-Dong, Brunnemann, Klaus D., Iatropoulos, Michael J., Vock, Esther, Deschl, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
DNA Adducts and Liver Carcinogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833110/
https://ncbi.nlm.nih.gov/pubmed/24973097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfu123
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