Chemical carcinogen safety testing: OECD expert group international consensus on the development of an integrated approach for the testing and assessment of chemical non-genotoxic carcinogens

While regulatory requirements for carcinogenicity testing of chemicals vary according to product sector and regulatory jurisdiction, the standard approach starts with a battery of genotoxicity tests (which include mutagenicity assays). If any of the in vivo genotoxicity tests are positive, a lifetim...

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Detalhes bibliográficos
Publicado no:Arch Toxicol
Main Authors: Jacobs, Miriam N., Colacci, Annamaria, Corvi, Raffaella, Vaccari, Monica, Aguila, M. Cecilia, Corvaro, Marco, Delrue, Nathalie, Desaulniers, Daniel, Ertych, Norman, Jacobs, Abigail, Luijten, Mirjam, Madia, Federica, Nishikawa, Akiyoshi, Ogawa, Kumiko, Ohmori, Kiyomi, Paparella, Martin, Sharma, Anoop Kumar, Vasseur, Paule
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2020
Assuntos:
Meeting Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7395040/
https://ncbi.nlm.nih.gov/pubmed/32594184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-020-02784-5
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