An interim report on the investigator-initiated phase 2 study of pembrolizumab immunological response evaluation (INSPIRE)

BACKGROUND: Immune checkpoint inhibitors (ICIs) demonstrate unprecedented efficacy in multiple malignancies; however, the mechanisms of sensitivity and resistance are poorly understood and predictive biomarkers are scarce. INSPIRE is a phase 2 basket study to evaluate the genomic and immune landscap...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:J Immunother Cancer
Hoofdauteurs: Clouthier, Derek L., Lien, Scott C., Yang, S. Y. Cindy, Nguyen, Linh T., Manem, Venkata S. K., Gray, Diana, Ryczko, Michael, Razak, Albiruni R. A., Lewin, Jeremy, Lheureux, Stephanie, Colombo, Ilaria, Bedard, Philippe L., Cescon, David, Spreafico, Anna, Butler, Marcus O., Hansen, Aaron R., Jang, Raymond W., Ghai, Sangeet, Weinreb, Ilan, Sotov, Valentin, Gadalla, Ramy, Noamani, Babak, Guo, Mengdi, Elston, Sawako, Giesler, Amanda, Hakgor, Sevan, Jiang, Haiyan, McGaha, Tracy, Brooks, David G., Haibe-Kains, Benjamin, Pugh, Trevor J., Ohashi, Pamela S., Siu, Lillian L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2019
Onderwerpen:
Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6417194/
https://ncbi.nlm.nih.gov/pubmed/30867072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-019-0541-0
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items