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DNA replication stress: a source of APOBEC3B expression in breast cancer

APOBEC cytidine deaminases have been implicated as major contributors to the mutation burden in many cancers on the basis of their mutational signature. A new experimental study sheds light on the inciting factors, linking APOBEC3B expression to oncogene- and drug-induced replication stress. ELECTRO...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Cescon, David W., Haibe-Kains, Benjamin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5045630/
https://ncbi.nlm.nih.gov/pubmed/27716362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-1069-y
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