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Structure, mechanism and therapeutic utility of immunosuppressive oligonucleotides

Synthetic oligodeoxynucleotides that can down-regulate cellular elements of the immune system have been developed and are being widely studied in preclinical models. These agents vary in sequence, mechanism of action, and cellular target(s) but share the ability to suppress a plethora of inflammator...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Pharmacol Res
Hauptverfasser: Bayik, Defne, Gursel, Ihsan, Klinman, Dennis M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6417099/
https://ncbi.nlm.nih.gov/pubmed/26779666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2015.11.010
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