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Structure, mechanism and therapeutic utility of immunosuppressive oligonucleotides

Synthetic oligodeoxynucleotides that can down-regulate cellular elements of the immune system have been developed and are being widely studied in preclinical models. These agents vary in sequence, mechanism of action, and cellular target(s) but share the ability to suppress a plethora of inflammator...

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Detalhes bibliográficos
Publicado no:Pharmacol Res
Main Authors: Bayik, Defne, Gursel, Ihsan, Klinman, Dennis M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6417099/
https://ncbi.nlm.nih.gov/pubmed/26779666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2015.11.010
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