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Structure, mechanism and therapeutic utility of immunosuppressive oligonucleotides

Synthetic oligodeoxynucleotides that can down-regulate cellular elements of the immune system have been developed and are being widely studied in preclinical models. These agents vary in sequence, mechanism of action, and cellular target(s) but share the ability to suppress a plethora of inflammator...

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Bibliografiska uppgifter
I publikationen:Pharmacol Res
Huvudupphovsmän: Bayik, Defne, Gursel, Ihsan, Klinman, Dennis M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6417099/
https://ncbi.nlm.nih.gov/pubmed/26779666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2015.11.010
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