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Structure, mechanism and therapeutic utility of immunosuppressive oligonucleotides

Synthetic oligodeoxynucleotides that can down-regulate cellular elements of the immune system have been developed and are being widely studied in preclinical models. These agents vary in sequence, mechanism of action, and cellular target(s) but share the ability to suppress a plethora of inflammator...

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Библиографические подробности
Опубликовано в: :Pharmacol Res
Главные авторы: Bayik, Defne, Gursel, Ihsan, Klinman, Dennis M.
Формат: Artigo
Язык:Inglês
Опубликовано: 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6417099/
https://ncbi.nlm.nih.gov/pubmed/26779666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2015.11.010
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