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Oxidation of methionine residues in human apolipoprotein A-I generates a potent pro-inflammatory molecule
Amyloid deposits of apolipoprotein A-I (apoA-I) and inflammation are common in atherosclerotic arteries. In this study, we investigated the interplay between oxidation of apoA-I methionine residues (Met(O)-ApoA-I), a known amyloidogenic modification of apoA-I, and the inflammatory response of immune...
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| Опубликовано в: : | J Biol Chem |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6416445/ https://ncbi.nlm.nih.gov/pubmed/30635405 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005663 |
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