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Methionine oxidation impairs reverse cholesterol transport by apolipoprotein A-I

HDL protects against vascular disease by accepting free cholesterol from macrophage foam cells in the artery wall. This pathway is critically dependent on lecithin:cholesterol acyltransferase (LCAT), which rapidly converts cholesterol to cholesteryl ester. The physiological activator of LCAT is apol...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Shao, Baohai, Cavigiolio, Giorgio, Brot, Nathan, Oda, Michael N., Heinecke, Jay W.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2008
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527893/
https://ncbi.nlm.nih.gov/pubmed/18719109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802025105
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