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Methionine oxidation impairs reverse cholesterol transport by apolipoprotein A-I
HDL protects against vascular disease by accepting free cholesterol from macrophage foam cells in the artery wall. This pathway is critically dependent on lecithin:cholesterol acyltransferase (LCAT), which rapidly converts cholesterol to cholesteryl ester. The physiological activator of LCAT is apol...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2527893/ https://ncbi.nlm.nih.gov/pubmed/18719109 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802025105 |
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