CNS-derived extracellular vesicles from superoxide dismutase 1 (SOD1)(G93A) ALS mice originate from astrocytes and neurons and carry misfolded SOD1

Extracellular vesicles (EVs) are secreted by myriad cells in culture and also by unicellular organisms, and their identification in mammalian fluids suggests that EV release also occurs at the organism level. However, although it is clearly important to better understand EVs' roles in organisma...

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Vydáno v:J Biol Chem
Hlavní autoři: Silverman, Judith M., Christy, Darren, Shyu, Chih Cheih, Moon, Kyung-Mee, Fernando, Sarah, Gidden, Zoe, Cowan, Catherine M., Ban, Yuxin, Stacey, R. Greg, Grad, Leslie I., McAlary, Luke, Mackenzie, Ian R., Foster, Leonard J., Cashman, Neil R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2019
Témata:
Neurobiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6416428/
https://ncbi.nlm.nih.gov/pubmed/30635404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004825
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