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Steered molecular dynamic simulations of conformational lock of Cu, Zn-superoxide dismutase
The conformational lock was a bio-thermodynamic theory to explain the characteristics of interfaces in oligomeric enzymes and their effects on catalytic activity. The previous studies on superoxide dismutases (Cu, Zn-SODs) showed that the dimeric structure contributed to the high catalytic efficienc...
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| Veröffentlicht in: | Sci Rep |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6416402/ https://ncbi.nlm.nih.gov/pubmed/30867507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-40892-0 |
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