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Steered molecular dynamic simulations of conformational lock of Cu, Zn-superoxide dismutase

The conformational lock was a bio-thermodynamic theory to explain the characteristics of interfaces in oligomeric enzymes and their effects on catalytic activity. The previous studies on superoxide dismutases (Cu, Zn-SODs) showed that the dimeric structure contributed to the high catalytic efficienc...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Xiao, Bao-Lin, Ning, Yan-Na, Niu, Nan-Nan, Li, Di, Moosavi-Movahedi, Ali Akbar, Sheibani, Nader, Hong, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6416402/
https://ncbi.nlm.nih.gov/pubmed/30867507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-40892-0
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