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Network-based prediction of drug combinations

Drug combinations, offering increased therapeutic efficacy and reduced toxicity, play an important role in treating multiple complex diseases. Yet, our ability to identify and validate effective combinations is limited by a combinatorial explosion, driven by both the large number of drug pairs as we...

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Bibliografiska uppgifter
I publikationen:Nat Commun
Huvudupphovsmän: Cheng, Feixiong, Kovács, István A., Barabási, Albert-László
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6416394/
https://ncbi.nlm.nih.gov/pubmed/30867426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09186-x
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