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Network-based prediction of drug combinations

Drug combinations, offering increased therapeutic efficacy and reduced toxicity, play an important role in treating multiple complex diseases. Yet, our ability to identify and validate effective combinations is limited by a combinatorial explosion, driven by both the large number of drug pairs as we...

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Publicat a:Nat Commun
Autors principals: Cheng, Feixiong, Kovács, István A., Barabási, Albert-László
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6416394/
https://ncbi.nlm.nih.gov/pubmed/30867426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09186-x
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