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Crystal structures of multidrug efflux pump MexB bound with high-molecular-mass compounds
RND-type multidrug efflux pumps have two voluminous multisite drug-binding pockets named the proximal and distal binding pocket. High- and low-molecular-mass drugs bind to these proximal and distal pocket, respectively. Here, we report the crystal structures of MexB of Pseudomonas aeruginosa bound w...
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| Veröffentlicht in: | Sci Rep |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6416280/ https://ncbi.nlm.nih.gov/pubmed/30867446 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-40232-2 |
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