Epithelial boost enhances antigen expression by vaccinia virus for the generation of potent CD8+ T cell-mediated antitumor immunity following DNA priming vaccination

While both pNGVL4a-Sig/E7(detox)/HSP70 DNA vaccine and TA-HPV recombinant vaccinia viral vector-based vaccines have elicited HPV-specific CD8+ T cell responses in HPV16/E7-expressing tumor models, and been used as prime-boost regimen to enhance HPV-specific immune responses in humans (NCT00788164),...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Virology
Prif Awduron: Qiu, Jin, Peng, Shiwen, Ma, Ying, Yang, Andrew, Farmer, Emily, Cheng, Max A., Roden, Richard B.S., Wu, T.-C., Chang, Yung-Nien, Hung, Chien-Fu
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6415901/
https://ncbi.nlm.nih.gov/pubmed/30296681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2018.09.019
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