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Local HPV Recombinant Vaccinia Boost Following Priming with an HPV DNA Vaccine Enhances Local HPV-Specific CD8+ T Cell Mediated Tumor Control in the Genital Tract
PURPOSE: Two viral oncoproteins, E6 and E7, are expressed in all human papillomavirus (HPV)-infected cells, from initial infection in the genital tract to metastatic cervical cancer. Intramuscular vaccination of women with high grade cervical intraepithelial neoplasia (CIN2/3) twice with a naked DNA...
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Udgivet i: | Clin Cancer Res |
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Main Authors: | , , , , , , , , , , |
Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
2015
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4738102/ https://ncbi.nlm.nih.gov/pubmed/26420854 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-0234 |
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