Optimization of heterologous DNA-prime, protein boost regimens and site of vaccination to enhance therapeutic immunity against human papillomavirus-associated disease

BACKGROUND: Human papillomavirus (HPV) has been identified as the primary etiologic factor of cervical cancer as well as subsets of anogenital and oropharyngeal cancers. The two HPV viral oncoproteins, E6 and E7, are uniquely and consistently expressed in all HPV infected cells and are therefore pro...

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Publicado en:Cell Biosci
Main Authors: Peng, Shiwen, Qiu, Jin, Yang, Andrew, Yang, Benjamin, Jeang, Jessica, Wang, Joshua W., Chang, Yung-Nien, Brayton, Cory, Roden, Richard B. S., Hung, Chien-Fu, Wu, T.-C.
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2016
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4766698/
https://ncbi.nlm.nih.gov/pubmed/26918115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-016-0080-z
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