Chronic treatment with the mitochondrial peptide humanin prevents age-related myocardial fibrosis in mice

Cardiac fibrosis is a biological process that increases with age and contributes to myocardial dysfunction. Humanin (HN) is an endogenous mitochondria-derived peptide that has cytoprotective effects and reduces oxidative stress. The present study aimed to test the hypothesis that chronic supplementa...

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Pubblicato in:Am J Physiol Heart Circ Physiol
Autori principali: Qin, Qing, Mehta, Hemal, Yen, Kelvin, Navarrete, Gerardo, Brandhorst, Sebastian, Wan, Junxiang, Delrio, Silvia, Zhang, Xin, Lerman, Lilach O., Cohen, Pinchas, Lerman, Amir
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2018
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6415743/
https://ncbi.nlm.nih.gov/pubmed/30004252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00685.2017
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