The mitochondrial derived peptide humanin is a regulator of lifespan and healthspan

Humanin is a member of a new family of peptides that are encoded by short open reading frames within the mitochondrial genome. It is conserved in animals and is both neuroprotective and cytoprotective. Here we report that in C. elegans the overexpression of humanin is sufficient to increase lifespan...

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Detaylı Bibliyografya
Yayımlandı:Aging (Albany NY)
Asıl Yazarlar: Yen, Kelvin, Mehta, Hemal H., Kim, Su-Jeong, Lue, YanHe, Hoang, James, Guerrero, Noel, Port, Jenna, Bi, Qiuli, Navarrete, Gerardo, Brandhorst, Sebastian, Lewis, Kaitlyn Noel, Wan, Junxiang, Swerdloff, Ronald, Mattison, Julie A., Buffenstein, Rochelle, Breton, Carrie V., Wang, Christina, Longo, Valter, Atzmon, Gil, Wallace, Douglas, Barzilai, Nir, Cohen, Pinchas
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals 2020
Konular:
Priority Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7343442/
https://ncbi.nlm.nih.gov/pubmed/32575074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103534
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