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Skeletal inflammation and attenuation of Wnt signaling, Wnt ligand expression, and bone formation in atherosclerotic ApoE-null mice

ApoE-null (ApoE-KO) mice fed a high-fat diet (HFD) develop atherosclerosis, due in part to activation of vascular inflammation by oxidized low-density lipoprotein. Since bone loss also occurs in these mice, we used them to investigate the impact of oxidized lipids on bone homeostasis and to search f...

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Bibliografiska uppgifter
I publikationen:Am J Physiol Endocrinol Metab
Huvudupphovsmän: Liu, Yu, Almeida, Maria, Weinstein, Robert S., O'Brien, Charles A., Manolagas, Stavros C., Jilka, Robert L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Physiological Society 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6415649/
https://ncbi.nlm.nih.gov/pubmed/26956187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00501.2015
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