Ciliary gene RPGRIP1L is required for hypothalamic arcuate neuron development

Intronic polymorphisms in the α-ketoglutarate–dependent dioxygenase gene (FTO) that are highly associated with increased body weight have been implicated in the transcriptional control of a nearby ciliary gene, retinitis pigmentosa GTPase regulator-interacting protein-1 like (RPGRIP1L). Previous stu...

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Détails bibliographiques
Publié dans:JCI Insight
Auteurs principaux: Wang, Liheng, De Solis, Alain J., Goffer, Yossef, Birkenbach, Kathryn E., Engle, Staci E., Tanis, Ross, Levenson, Jacob M., Li, Xueting, Rausch, Richard, Purohit, Manika, Lee, Jen-Yi, Tan, Jerica, De Rosa, Maria Caterina, Doege, Claudia A., Aaron, Holly L., Martins, Gabriela J., Brüning, Jens C., Egli, Dieter, Costa, Rui, Berbari, Nicolas, Leibel, Rudolph L., Stratigopoulos, George
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2019
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6413800/
https://ncbi.nlm.nih.gov/pubmed/30728336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.123337
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