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Targeting mGlu Receptors for Optimization of Antipsychotic Activity and Disease-Modifying Effect in Schizophrenia
Metabotropic glutamate (mGlu) receptors are considered as candidate drug targets for the treatment of schizophrenia. These receptors form a family of eight subtypes (mGlu1 to −8), of which mGlu1 and −5 are coupled to G(q/11), and all other subtypes are coupled to G(i/o). Here, we discuss the possibi...
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| Wydane w: | Front Psychiatry |
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| Główni autorzy: | , , , , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Frontiers Media S.A.
2019
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6413697/ https://ncbi.nlm.nih.gov/pubmed/30890967 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fpsyt.2019.00049 |
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