Microglial Cell Activation and Senescence are Characteristic of the Pathology FXTAS

BACKGROUND: Fragile X-associated tremor/ataxia syndrome (FXTAS) is a late-onset neurodegenerative disorder associated with premutation alleles of the FMR1 gene. Expansions of more than 200 CGG repeats give rise to fragile X syndrome, the most common inherited form of cognitive impairment. Fragile X-...

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Vydáno v:Mov Disord
Hlavní autoři: Cerdeño, Verónica Martínez, Hong, Tiffany, Amina, Sarwat, Lechpammer, Mirna, Ariza, Jeanelle, Tassone, Flora, Noctor, Stephen C., Hagerman, Paul, Hagerman, Randi
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6413690/
https://ncbi.nlm.nih.gov/pubmed/30537011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mds.27553
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