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Dietary restriction and gonadal signaling differentially regulate post‐development quality control functions in Caenorhabditis elegans

Protein homeostasis is remodeled early in Caenorhabditis elegans adulthood, resulting in a sharp decline in folding capacity and reduced ability to cope with chronic and acute stress. Endocrine signals from the reproductive system can ameliorate this proteostatic collapse and reshape the quality con...

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Detalhes bibliográficos
Publicado no:Aging Cell
Principais autores: Shpigel, Nufar, Shemesh, Netta, Kishner, Mor, Ben‐Zvi, Anat
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6413660/
https://ncbi.nlm.nih.gov/pubmed/30648346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12891
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