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Dietary restriction and gonadal signaling differentially regulate post‐development quality control functions in Caenorhabditis elegans

Protein homeostasis is remodeled early in Caenorhabditis elegans adulthood, resulting in a sharp decline in folding capacity and reduced ability to cope with chronic and acute stress. Endocrine signals from the reproductive system can ameliorate this proteostatic collapse and reshape the quality con...

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Pubblicato in:Aging Cell
Autori principali: Shpigel, Nufar, Shemesh, Netta, Kishner, Mor, Ben‐Zvi, Anat
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6413660/
https://ncbi.nlm.nih.gov/pubmed/30648346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12891
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