Differential Effects of the Absence of Nkx2-3 and MAdCAM-1 on the Distribution of Intestinal Type 3 Innate Lymphoid Cells and Postnatal SILT Formation in Mice

Seeding of leukocytes to developing lymphoid tissues in embryonic and early postnatal age and to the mucosa throughout adulthood depends on the interaction between endothelial MAdCAM-1 addressin and its cognate ligand α4β7 integrin. Nkx2-3 as a transcriptional regulator of MAdCAM-1 controls vascular...

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Bibliographische Detailangaben
Veröffentlicht in:Front Immunol
Hauptverfasser: Vojkovics, Dóra, Kellermayer, Zoltán, Gábris, Fanni, Schippers, Angela, Wagner, Norbert, Berta, Gergely, Farkas, Kornélia, Balogh, Péter
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6413488/
https://ncbi.nlm.nih.gov/pubmed/30891037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00366
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