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NKX2.3 is required for MAdCAM-1 expression and homing of lymphocytes in spleen and mucosa-associated lymphoid tissue

Targeted disruption of the transcription factor NKX2.3 gene in mice results in anatomical defects of intestine and secondary lymphoid organs. Here, we report that spleen and Peyer’s patches of NKX2.3-deficient mice are considerably reduced in size and lack the ordered tissue architecture. T and B ce...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Pabst, Oliver, Förster, Reinhold, Lipp, Martin, Engel, Holger, Arnold, Hans-Henning
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2000
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC305695/
https://ncbi.nlm.nih.gov/pubmed/10790368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.9.2015
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