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NKX2.3 is required for MAdCAM-1 expression and homing of lymphocytes in spleen and mucosa-associated lymphoid tissue

Targeted disruption of the transcription factor NKX2.3 gene in mice results in anatomical defects of intestine and secondary lymphoid organs. Here, we report that spleen and Peyer’s patches of NKX2.3-deficient mice are considerably reduced in size and lack the ordered tissue architecture. T and B ce...

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Detalhes bibliográficos
Main Authors: Pabst, Oliver, Förster, Reinhold, Lipp, Martin, Engel, Holger, Arnold, Hans-Henning
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC305695/
https://ncbi.nlm.nih.gov/pubmed/10790368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.9.2015
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