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NKX2.3 is required for MAdCAM-1 expression and homing of lymphocytes in spleen and mucosa-associated lymphoid tissue

Targeted disruption of the transcription factor NKX2.3 gene in mice results in anatomical defects of intestine and secondary lymphoid organs. Here, we report that spleen and Peyer’s patches of NKX2.3-deficient mice are considerably reduced in size and lack the ordered tissue architecture. T and B ce...

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Библиографические подробности
Главные авторы: Pabst, Oliver, Förster, Reinhold, Lipp, Martin, Engel, Holger, Arnold, Hans-Henning
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2000
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC305695/
https://ncbi.nlm.nih.gov/pubmed/10790368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.9.2015
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