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NKX2.3 is required for MAdCAM-1 expression and homing of lymphocytes in spleen and mucosa-associated lymphoid tissue
Targeted disruption of the transcription factor NKX2.3 gene in mice results in anatomical defects of intestine and secondary lymphoid organs. Here, we report that spleen and Peyer’s patches of NKX2.3-deficient mice are considerably reduced in size and lack the ordered tissue architecture. T and B ce...
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| Опубликовано в: : | EMBO J |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2000
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC305695/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10790368/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.9.2015 |
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