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Arsenic trioxide inhibits Skp2 expression to increase chemosensitivity to gemcitabine in pancreatic cancer cells

The S-phase kinase associated protein 2 (Skp2), a member of the F-box protein family, regulates cell cycle progression and is highly expressed in pancreatic cancer (PC). Recently, we reported that arsenic trioxide (ATO) inhibited cell growth and invasion via downregulation of Skp2 in PC cells. Emerg...

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Detalhes bibliográficos
Publicado no:Am J Transl Res
Main Authors: Gao, Jiankun, Wang, Gu, Wu, Jingrong, Zuo, Yu, Zhang, Jing, Chen, Jiaqi
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6413247/
https://ncbi.nlm.nih.gov/pubmed/30899398
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