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LW6 enhances chemosensitivity to gemcitabine and inhibits autophagic flux in pancreatic cancer

The efficacy of gemcitabine therapy is often insufficient for the treatment of pancreatic cancer. The current study demonstrated that LW6, a chemical inhibitor of hypoxia-inducible factor 1α, is a promising drug for enhancing the chemosensitivity to gemcitabine. LW6 monotherapy and the combination t...

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Detalhes bibliográficos
Publicado no:J Adv Res
Main Authors: Zhang, Xianbin, Kumstel, Simone, Jiang, Ke, Meng, Songshu, Gong, Peng, Vollmar, Brigitte, Zechner, Dietmar
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6514270/
https://ncbi.nlm.nih.gov/pubmed/31193017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jare.2019.04.006
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