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Chemosensitivity enhancement toward arsenic trioxide by inhibition of histone deacetylase in NB4 cell line

OBJECTIVE: To investigate the cytotoxic effects of suberanilohydroxamic acid (vorinostat) in combination with arsenic trioxide (ATO) on the human NB4 cell line in vitro. METHODS: The rates of cell proliferation following treatment with vorinostat with or without ATO were measured. Flow cytometry of...

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Detalhes bibliográficos
Publicado no:J Int Med Res
Main Authors: Li, Xiaofan, Guan, Xiaoyan, Li, Fang, Chen, Yuanzhong, Li, Nainong
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5536622/
https://ncbi.nlm.nih.gov/pubmed/27189198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0300060516646238
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