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Vorinostat enhances chemosensitivity to arsenic trioxide in K562 cell line

Objective. This study aimed to investigate the chemosensitive augmentation effect and mechanism of HDAC inhibitor Vorinostat (SAHA) in combination with arsenic trioxide (ATO) on proliferation and apoptosis of K562 cells. Methods. The CCK-8 assay was used to compare proliferation of the cells. Annexi...

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Detalhes bibliográficos
Publicado no:PeerJ
Main Authors: Li, Nainong, Guan, Xiaoyan, Li, Fang, Li, Xiaofan, Chen, Yuanzhong
Formato: Artigo
Idioma:Inglês
Publicado em: PeerJ Inc. 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4451029/
https://ncbi.nlm.nih.gov/pubmed/26038719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.962
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