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Targeting Catalase but Not Peroxiredoxins Enhances Arsenic Trioxide-Induced Apoptosis in K562 Cells
Despite considerable efficacy of arsenic trioxide (As(2)O(3)) in acute promyelocytic leukemia (APL) treatment, other non-APL leukemias, such as chronic myeloid leukemia (CML), are less sensitive to As(2)O(3) treatment. However, the underlying mechanism is not well understood. Here we show that relat...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4130628/ https://ncbi.nlm.nih.gov/pubmed/25115845 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0104985 |
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