Targeting Catalase but Not Peroxiredoxins Enhances Arsenic Trioxide-Induced Apoptosis in K562 Cells

Despite considerable efficacy of arsenic trioxide (As(2)O(3)) in acute promyelocytic leukemia (APL) treatment, other non-APL leukemias, such as chronic myeloid leukemia (CML), are less sensitive to As(2)O(3) treatment. However, the underlying mechanism is not well understood. Here we show that relat...

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Bibliografiske detaljer
Main Authors: Song, Li-Li, Tu, Yao-Yao, Xia, Li, Wang, Wei-Wei, Wei, Wei, Ma, Chun-Min, Wen, Dong-Hua, Lei, Hu, Xu, Han-Zhang, Wu, Ying-Li
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4130628/
https://ncbi.nlm.nih.gov/pubmed/25115845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0104985
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