Genome-wide siRNA screening in mouse bone marrow-derived macrophages revealed that knockdown of ribosomal proteins suppresses IL-10 and enhances TNF-α production.

Macrophages play a central role in the immune response, and their diverse functions are attributed to the spectrum of their functional states. To elucidate molecules involved in modulating the balance between the anti-inflammatory cytokine IL-10 and the pro-inflammatory cytokine TNF-α, we conducted...

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Bibliographische Detailangaben
Veröffentlicht in:J Clin Exp Hematop
Hauptverfasser: Okamura, Yoshihiko, Makita, Naoyuki, Hizukuri, Yoshiyuki, Hayashi, Yasuhiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: JSLRT 2018
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6413152/
https://ncbi.nlm.nih.gov/pubmed/29657255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3960/jslrt.17036
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