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Further Probing of Cu(2+)-Dependent PNAzymes Acting as Artificial RNA Restriction Enzymes

Peptide nucleic acid (PNA)-neocuproine conjugates have been shown to efficiently catalyse the cleavage of RNA target sequences in the presence of Cu(2+) ions in a site-specific manner. These artificial enzymes are designed to force the formation of a bulge in the RNA target, the sequence of which ha...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Molecules
Hauptverfasser: Luige, Olivia, Murtola, Merita, Ghidini, Alice, Strömberg, Roger
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6412939/
https://ncbi.nlm.nih.gov/pubmed/30769777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24040672
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