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Modulation of Obesity and Insulin Resistance by the Redox Enzyme and Adaptor Protein p66(Shc)

Initially reported as a longevity-related protein, the 66 kDa isoform of the mammalian Shc1 locus has been implicated in several metabolic pathways, being able to act both as an adaptor protein and as a redox enzyme capable of generating reactive oxygen species (ROS) when it localizes to the mitocho...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Ciciliot, Stefano, Fadini, Gian Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6412263/
https://ncbi.nlm.nih.gov/pubmed/30813483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20040985
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