Mammalian life-span determinant p66(shcA) mediates obesity-induced insulin resistance

Obesity and metabolic syndrome result from excess calorie intake and genetic predisposition and are mechanistically linked to type II diabetes and accelerated body aging; abnormal nutrient and insulin signaling participate in this pathologic process, yet the underlying molecular mechanisms are incom...

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Bibliografiska uppgifter
Huvudupphovsmän: Ranieri, Sofia Chiatamone, Fusco, Salvatore, Panieri, Emiliano, Labate, Valentina, Mele, Marina, Tesori, Valentina, Ferrara, Anna Maria, Maulucci, Giuseppe, De Spirito, Marco, Martorana, Giuseppe Ettore, Galeotti, Tommaso, Pani, Giovambattista
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2010
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922173/
https://ncbi.nlm.nih.gov/pubmed/20624962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1008647107
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