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Mammalian life-span determinant p66(shcA) mediates obesity-induced insulin resistance
Obesity and metabolic syndrome result from excess calorie intake and genetic predisposition and are mechanistically linked to type II diabetes and accelerated body aging; abnormal nutrient and insulin signaling participate in this pathologic process, yet the underlying molecular mechanisms are incom...
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| Autores principales: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2922173/ https://ncbi.nlm.nih.gov/pubmed/20624962 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1008647107 |
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