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Low Electric Treatment activates Rho GTPase via Heat Shock Protein 90 and Protein Kinase C for Intracellular Delivery of siRNA

Low electric treatment (LET) promotes intracellular delivery of naked siRNA by altering cellular physiology. However, which signaling molecules and cellular events contribute to LET-mediated siRNA uptake are unclear. Here, we used isobaric tags in relative and absolute quantification (iTRAQ) proteom...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Hasan, Mahadi, Hama, Susumu, Kogure, Kentaro
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6412017/
https://ncbi.nlm.nih.gov/pubmed/30858501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-40904-z
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