Histone demethylase KDM3A is required for enhancer activation of hippo target genes in colorectal cancer

Hippo pathway is involved in tumorigenesis, and its regulation in cytosol has been extensively studied, but its regulatory mechanisms in the nuclear are not clear. In the current study, using a FBS-inducing model following serum starvation, we identified KDM3A, a demethylase of histone H3K9me1/2, as...

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Detaylı Bibliyografya
Yayımlandı:Nucleic Acids Res
Asıl Yazarlar: Wang, Hui-Yi, Long, Qiao-Yun, Tang, Shan-Bo, Xiao, Qiong, Gao, Chuan, Zhao, Quan-Yi, Li, Qing-Lan, Ye, Mei, Zhang, Lei, Li, Lian-Yun, Wu, Min
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2019
Konular:
Gene regulation, Chromatin and Epigenetics
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6412006/
https://ncbi.nlm.nih.gov/pubmed/30649550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky1317
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