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Histone demethylase KDM3A is required for enhancer activation of hippo target genes in colorectal cancer

Hippo pathway is involved in tumorigenesis, and its regulation in cytosol has been extensively studied, but its regulatory mechanisms in the nuclear are not clear. In the current study, using a FBS-inducing model following serum starvation, we identified KDM3A, a demethylase of histone H3K9me1/2, as...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Wang, Hui-Yi, Long, Qiao-Yun, Tang, Shan-Bo, Xiao, Qiong, Gao, Chuan, Zhao, Quan-Yi, Li, Qing-Lan, Ye, Mei, Zhang, Lei, Li, Lian-Yun, Wu, Min
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6412006/
https://ncbi.nlm.nih.gov/pubmed/30649550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky1317
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