Histone demethylase KDM3A is required for enhancer activation of hippo target genes in colorectal cancer

Hippo pathway is involved in tumorigenesis, and its regulation in cytosol has been extensively studied, but its regulatory mechanisms in the nuclear are not clear. In the current study, using a FBS-inducing model following serum starvation, we identified KDM3A, a demethylase of histone H3K9me1/2, as...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Wang, Hui-Yi, Long, Qiao-Yun, Tang, Shan-Bo, Xiao, Qiong, Gao, Chuan, Zhao, Quan-Yi, Li, Qing-Lan, Ye, Mei, Zhang, Lei, Li, Lian-Yun, Wu, Min
Format: Artigo
Language:Inglês
Published: Oxford University Press 2019
Subjects:
Gene regulation, Chromatin and Epigenetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6412006/
https://ncbi.nlm.nih.gov/pubmed/30649550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky1317
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