Heme promotes transcriptional and demethylase activities of Gis1, a member of the histone demethylase JMJD2/KDM4 family

The yeast Gis1 protein is a transcriptional regulator belonging to the JMJD2/KDM4 subfamily of demethylases that contain a JmjC domain, which are highly conserved from yeast to humans. They have important functions in histone methylation, cellular signaling and tumorigenesis. Besides serving as a co...

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Bibliografske podrobnosti
izdano v:Nucleic Acids Res
Main Authors: Lal, Sneha, Comer, Jonathan M, Konduri, Purna C, Shah, Ajit, Wang, Tianyuan, Lewis, Anthony, Shoffner, Grant, Guo, Feng, Zhang, Li
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2018
Teme:
Gene regulation, Chromatin and Epigenetics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5758875/
https://ncbi.nlm.nih.gov/pubmed/29126261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1051
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