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ADP-Ribose and oxidative stress activate TRPM8 channel in prostate cancer and kidney cells

Activation of TRPM8 channel through oxidative stress may induce Ca(2+) and pro-apoptotic signals in prostate cancer and kidney cells. The aim of this study was to evaluate activation of TRPM8 can increase apoptosis and oxidative stress in the prostate cancer (Du145(M8)), TRPM8 knock out (Du 145(M8KO...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Baş, Ercan, Nazıroğlu, Mustafa, Pecze, László
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6411746/
https://ncbi.nlm.nih.gov/pubmed/30858386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-37552-0
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