Anti-tumor activity of antibody drug conjugate targeting aspartate-β-hydroxylase in pancreatic ductal adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) is an extremely aggressive malignancy with very limited treatment options. Antibody drug conjugates (ADCs) are promising cytotoxic agents capable of highly selective delivery. Aspartate-β-hydroxylase (ASPH) is a type II transmembrane protein highly expressed i...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Cancer Lett
Hlavní autoři: Nagaoka, Katsuya, Bai, Xuewei, Ogawa, Kosuke, Dong, Xiaoqun, Zhang, Songhua, Zhou, Yanmei, Carlson, Rolf I., Jiang, Zhi-Gang, Fuller, Steve, Lebowitz, Michael S., Ghanbari, Hossein, Wands, Jack R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6411448/
https://ncbi.nlm.nih.gov/pubmed/30768955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2019.02.006
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky