Anti-tumor activity of antibody drug conjugate targeting aspartate-β-hydroxylase in pancreatic ductal adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) is an extremely aggressive malignancy with very limited treatment options. Antibody drug conjugates (ADCs) are promising cytotoxic agents capable of highly selective delivery. Aspartate-β-hydroxylase (ASPH) is a type II transmembrane protein highly expressed i...

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Dades bibliogràfiques
Publicat a:Cancer Lett
Autors principals: Nagaoka, Katsuya, Bai, Xuewei, Ogawa, Kosuke, Dong, Xiaoqun, Zhang, Songhua, Zhou, Yanmei, Carlson, Rolf I., Jiang, Zhi-Gang, Fuller, Steve, Lebowitz, Michael S., Ghanbari, Hossein, Wands, Jack R.
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6411448/
https://ncbi.nlm.nih.gov/pubmed/30768955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2019.02.006
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