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Maximum entropy and population heterogeneity in continuous cell cultures

Continuous cultures of mammalian cells are complex systems displaying hallmark phenomena of nonlinear dynamics, such as multi-stability, hysteresis, as well as sharp transitions between different metabolic states. In this context mathematical models may suggest control strategies to steer the system...

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Библиографические подробности
Опубликовано в: :PLoS Comput Biol
Главные авторы: Fernandez-de-Cossio-Diaz, Jorge, Mulet, Roberto
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6411232/
https://ncbi.nlm.nih.gov/pubmed/30811392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006823
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