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Cell population heterogeneity driven by stochastic partition and growth optimality

A fundamental question in biology is how cell populations evolve into different subtypes based on homogeneous processes at the single cell level. Here we show that population bimodality can emerge even when biological processes are homogenous at the cell level and the environment is kept constant. O...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Fernandez-de-Cossio-Diaz, Jorge, Mulet, Roberto, Vazquez, Alexei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6599024/
https://ncbi.nlm.nih.gov/pubmed/31253860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-45882-w
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